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Selank

Heptapeptide / Tuftsin Origin

Selank is a synthetic heptapeptide structurally derived from the endogenous immunopeptide tuftsin, with 135 indexed PubMed entries (44 human, 108 animal, 10 clinical) documenting its research literature.

Price range: $30.00 through $45.00

Selank is a synthetic analog of the immunomodulatory peptide Tuftsin, developed by the Institute of Molecular Genetics in Russia. It exerts anxiolytic effects comparable to benzodiazepines

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SKU: LL-SELANK Category:

PubMed Literature Index

135

studies indexed in the public literature

Q2 2026 · view PubMed search ↗

44
Human
108
Animal
10
Clinical Trials
0
EU Trials

Overview

In the literature, Selank is described as a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro), a stabilized analog of the endogenous immunopeptide tuftsin, with a C-terminal Pro-Gly-Pro extension reported to increase its resistance to enzymatic degradation. Studies describe it as having been developed at Russia's Institute of Molecular Genetics as a peptide-based anxiolytic research candidate intended to avoid the sedation, dependence, and tolerance profile associated with benzodiazepines. The proposed mechanism in the literature is indirect neuromodulation, with reported involvement in GABA-A receptor sensitivity and in serotonergic and dopaminergic signaling systems, rather than direct receptor agonism.

Chemical & Molecular Properties

FormulaC33H57N11O9
Mol. Weight751.9 g/mol
PubChem CID11765600

Key Areas of Research Interest

  • Investigated in the context of anxiolytic-related neuropharmacology research
  • Investigated in the context of GABA-A receptor sensitivity modulation
  • Investigated in the context of serotonergic and dopaminergic signaling
  • Investigated in the context of tuftsin-derived immunopeptide structure-activity relationships

FAQ

What is Selank commonly researched for?

Selank is studied in the research literature primarily in the context of anxiolytic-related neuropharmacology, including its reported involvement in GABA-A receptor sensitivity and serotonergic/dopaminergic signaling, as a stabilized structural analog of the immunopeptide tuftsin. It is sold strictly for laboratory research use.

Is Selank FDA-approved?

No. Sold for laboratory research use only, not FDA-approved, not for human or veterinary consumption.

How is Selank stored?

Lyophilized and frozen, protected from light; refrigerated after reconstitution for research use.

What purity standard does Legendary Labz hold Selank to?

Every lot of Selank is independently, third-party tested for purity prior to release.

Is a Certificate of Analysis available for Selank?

COAs are published per lot as testing completes.

Materials referenced on this page are intended for laboratory research purposes. No claims regarding therapeutic efficacy are made or implied. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.

Description

Overview

Selank is a synthetic analog of the immunomodulatory peptide Tuftsin, developed by the Institute of Molecular Genetics in Russia. It exerts anxiolytic effects comparable to benzodiazepines but without sedation, dependency, or cognitive impairment. It modulates GABA-A receptors, stabilizes enkephalins (endogenous opioid peptides), and normalizes serotonin pathways. It also has immune regulatory properties, used clinically in Russia for generalized anxiety disorder, depression with anxiety, and immune dysfunction.

Structure & Chemistry

  • Molecular formula: C₃₃H₅₇N₁₁O₉
  • Category: ANTI-ANXIETY / COGNITIVE
  • Molecular size: 751.9 Da (Synthetic heptapeptide, tuftsin analog)

Regulatory & Research Status

  • FDA: Not approved. Prescription anxiolytic in Russia (Selank nasal spray). No US IND or clinical trial registration.
  • WADA: Not currently prohibited.
  • Evidence: Russian clinical studies for GAD and anxiety disorders. Limited Western data. Benzodiazepine-comparable efficacy claims are from Russian clinical literature, not Western double-blind RCTs.

Specifications

Presentation 5mg or 10mg lyophilized peptide, single vial
Purity >99% by HPLC
Form Lyophilized powder (reconstitute with bacteriostatic water for laboratory use)
Category ANTI-ANXIETY / COGNITIVE
For laboratory and research use only. Not for human or animal consumption. Not approved by the FDA for any therapeutic use. No claims regarding therapeutic efficacy are made or implied. Must be 21 or older.

Additional information

Size

5mg, 10mg

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Overview

Selank is a synthetic analog of the immunomodulatory peptide Tuftsin, developed by the Institute of Molecular Genetics in Russia. It exerts anxiolytic effects comparable to benzodiazepines but without sedation, dependency, or cognitive impairment. It modulates GABA-A receptors, stabilizes enkephalins (endogenous opioid peptides), and normalizes serotonin pathways. It also has immune regulatory properties, used clinically in Russia for generalized anxiety disorder, depression with anxiety, and immune dysfunction.

Structure & Chemistry

  • Molecular formula: C₃₃H₅₇N₁₁O₉
  • Category: ANTI-ANXIETY / COGNITIVE
  • Molecular size: 751.9 Da (Synthetic heptapeptide, tuftsin analog)

Regulatory & Research Status

  • FDA: Not approved. Prescription anxiolytic in Russia (Selank nasal spray). No US IND or clinical trial registration.
  • WADA: Not currently prohibited.
  • Evidence: Russian clinical studies for GAD and anxiety disorders. Limited Western data. Benzodiazepine-comparable efficacy claims are from Russian clinical literature, not Western double-blind RCTs.

Specifications

Presentation 5mg or 10mg lyophilized peptide, single vial
Purity >99% by HPLC
Form Lyophilized powder (reconstitute with bacteriostatic water for laboratory use)
Category ANTI-ANXIETY / COGNITIVE
For laboratory and research use only. Not for human or animal consumption. Not approved by the FDA for any therapeutic use. No claims regarding therapeutic efficacy are made or implied. Must be 21 or older.

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