Description
Overview
5-Amino-1MQ is a small molecule inhibitor of NNMT (nicotinamide N-methyltransferase), an enzyme that consumes SAM and reduces NAD+ precursor availability in fat tissue. By blocking NNMT, 5-Amino-1MQ effectively reduces the metabolic efficiency of fat cells, making them less able to store energy, while simultaneously increasing cellular NAD+ levels. Animal studies show significant fat mass reduction without muscle loss, improved endurance, and metabolic enhancement.
Structure & Chemistry
- Molecular formula: C₁₀H₁₁N₂⁺ (cation)
- Category: FAT METABOLISM / NAD+ SUPPORT
- Molecular size: 178.2 Da (Small molecule NNMT inhibitor, not a peptide)
Regulatory & Research Status
- FDA: Not approved. Small molecule research compound. No clinical trials in humans initiated. Not a scheduled controlled substance.
- WADA: Not currently listed as prohibited.
- Evidence: Animal model data only (Neelakantan et al. 2019 Nat Comm). No human pharmacokinetic or efficacy trials completed.
Specifications
| Presentation | 50mg single vial |
|---|---|
| Purity | >99% by HPLC |
| Form | Lyophilized powder (reconstitute with bacteriostatic water for laboratory use) |
| Category | FAT METABOLISM / NAD+ SUPPORT |
For laboratory and research use only. Not for human or animal consumption. Not approved by the FDA for any therapeutic use. No claims regarding therapeutic efficacy are made or implied. Must be 21 or older.
Reviews
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